Alkoxide-induced nucleophilic trifluoromethylation using diethyl trifluoromethylphosphonate

作者：Cherkupally Prabhakar; Beier Petr^*

来源：Tetrahedron Letters, 2010, 51(2): 252-255.

DOI：10.1016/j.tetlet.2009.10.135

• Trifluoromethylation
• Phosphonate
• Nucleophilic addition

A novel alkoxide-induced nucleophilic trifluoromethylation of carbonyl compounds, disulfides and diselenides using diethyl trifluoromethylphosphonate is presented. In these reactions diethyl trifluoromethylphosphonate acts as a [CF3-] synthon.

• 出版日期2010-1-13