A new fatty acid ester from an edible mushroom Rhizopogon luteolus

作者：Tel Cayan Guelsen; Muhammad Akhtar; Duru Mehmet Emin^*; Ozturk Mehmet; Adhikari Achyut; Turkoglu Aziz

来源：Natural Product Research, 2016, 30(20): 2258-2264.

DOI：10.1080/14786419.2016.1160237

• Rhizopogon luteolus
• fatty acid
• ergosterol
• phenolic compounds
• antioxidant activity
• anticholinesterase activity

Phytochemical investigation of the Rhizopogon luteolus Fr. led to the isolation of one new fatty acid ester, 3-hydroxy-2,4-dimethylheptacosyl acetate (1) together with two knowncompounds tetracosanoic acid (2) and ergosterol (3). 1D and 2D NMR, and MS techniques were used for structural elucidation. Phenolic and fatty acid compositions were identified using HPLC-DAD and GC-MSD, respectively. Fumaric acid was the major phenolic acid, whereas linoleic, stearic and oleic acids were the most abundant fatty acids. Antioxidant and anticholinesterase activities of the extracts and compounds (1-3) were tested spectrophotometrically. Among the extracts, hexane extract showed the highest activity in all tests, particularly in -carotene-linoleic acid assay (IC50: 16.65 +/- 1.12g/mL). Furthermore, compound 3 exhibited higher antioxidant and anticholinesterase activities. The study indicates that R. luteolus can be used in food, cosmetic and pharmaceutical industries.
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• 出版日期2016