Amino Surface-Functionalized Tris(calix[4]arene) Dendrons with Rigid C-3-Symmetric Propeller Cores

作者：Gattuso Giuseppe; Grasso Giulia; Marino Nino; Notti Anna; Pappalardo Andrea; Pappalardo Sebastiano^*; Parisi Melchiorre F

来源：European Journal of Organic Chemistry, 2011, (28): 5696-5703.

DOI：10.1002/ejoc.201100812

• Supramolecular chemistry
• Calixarenes
• Dendrimers
• Tripodal ligands
• Amides

Special Section Dendrons composed of three functionalized cone calix[4]arene substructures covalently bound to rigid C-3-symmetric tris-anilino cores through amide linkages have been obtained by a divergent synthetic protocol involving the coupling of p-nitrocalix[4]arene butanoic acid 9 with tris(4-aminophenyl)amine (TAPA), 1,3,5-tris(4-aminophenyl)benzene (TAPB), and 2,4,6-tris(4-aminophenyl)-s-triazine (TAPT). Two different amidation procedures were used to generate the dodecanitro intermediates (through activation of acid 9 with PyBOP catalyst or transformation into its acid chloride). The final reduction to the title dodecaamino dendrons was smoothly carried out with H-2 and Raney-Ni catalyst.

• 出版日期2011-10