Anxiety and Depression Are Better Correlates of Parkinson's Disease Quality of Life Than Apathy

作者：Jones Jacob D; Butterfield London C; Song Woojin; Lafo Jacob; Mangal Paul; Okun Michael S; Bowers Dawn^*

来源：Journal of Neuropsychiatry and Clinical Neurosciences, 2015, 27(3): 213-218.

DOI：10.1176/appi.neuropsych.13120380

Due to controversy regarding the influence of apathy on quality of life (QoL), the authors examined the independent influence of apathy, depression, and trait anxiety in a nondemented sample of patients with Parkinson disease (PD). Participants (N=107) completed standard self-report measures of QoL and mood/motivation. Analyses investigated the contribution of these measures and empirically derived factor scores on QoL. QoL was predicted by trait anxiety, dysphoria, and decreased interest, with no independent contribution of apathy. Different patterns emerged with respect to domain-specific QoL, with trait anxiety being the strongest predictor across most domains. Anxiety was most widely related to QoL in PD, with minimal contribution of apathy. Future studies should examine different roles of PD mood/motivation symptoms on caregiver QoL.

• 出版日期2015