Mechanistic Insight into Transition Metal-Catalyzed Reaction of Enynal/Enynone with Alkenes: Metal-Dependent Reaction Pathway

作者：Zhu, Shifa^*; Huang, Hua; Zhang, Zhicai; Ma, Tongmei; Jiang, Huanfeng

来源：Journal of Organic Chemistry, 2014, 79(13): 6113-6122.

DOI：10.1021/jo500838x

• LEWIS-ACID
• O-QUINODIMETHANES
• 4+2 CYCLOADDITION
• DERIVATIVES
• BENZANNULATION
• 2-ALKYNYLBENZALDEHYDES
• CYCLIZATION
• CASCADE
• ALKYNES
• O-ALKYNYL(OXO)BENZENES

A systematic study of the transition metal-catalyzed reaction of enynal/enynone with alkenes has been reported. It was found that the reaction has two metal-dependent reaction pathways. One led to the formation of 1,2-DHN, while another led to cyclic-o-QDM.

• 出版日期2014-7-4
• 单位华南理工大学