A passive solid sensor for in-situ colorimetric estimation of the presence of ketamine in illicit drug samples

作者：Argente Garcia A; Jornet Martinez N; Herraez Hernandez R^*; Campins Falco P

来源：Sensors and Actuators B: Chemical , 2017, 253: 1137-1144.

DOI：10.1016/j.snb.2017.07.183

• Ketamine
• Cobalt (II) thiocyanate
• Colorimetric sensor
• On-site analysis
• Drug street samples

A colorimetric sensor has been developed for the presumptive detection of ketamine in illicit drug samples. The sensor has been prepared by immobilized the reagent Co(SCN)(2) into polydimethylsiloxane (PDMS). When exposed to solutions of ketamine at a basic pH, the sensor color changes from brown to blue-purple due to the diffusion of the analyte molecules to the polymeric matrix and subsequent interaction with the reagent particles. The sensor enables the visual identification of amounts of drug as low as 30 tig in a few minutes. Quantification of ketamine is also possible through the measurement of the absorbance in diffuse reflectance mode. Under the proposed conditions, linear response was obtained up to concentrations of the ketamine of 1000 tigimL (4.21 mM) with satisfactory precision (relative standard deviations, RDSs <10%). The reliability of the developed sensors has been tested by analyzing illicit drug samples. The tested samples were also processed by Fourier transform infrared-attenuated total reflectance (FTIR-ATR) and liquid chromatography (LC) for comparison purposes.

• 出版日期2017-12