Nitroxide-Mediated Radical Ring-Opening Copolymerization: Chain-End Investigation and Block Copolymer Synthesis

作者：Delplace Vianney; Harrisson Simon; Tardy Antoine; Gigmes Didier; Guillaneuf Yohann; Nicolas Julien^*

来源：Macromolecular Rapid Communications, 2014, 35(4): 484-491.

DOI：10.1002/marc.201300809

• biodegradable
• block copolymer
• kinetics (polym
• )
• living polymerization
• nitroxide-mediated polymerization (NMP)

Well-defined, degradable copolymers are successfully prepared by nitroxide-mediated radical ring opening polymerization (NMrROP) of oligo(ethylene glycol) methyl ether methacrylate (OEGMA) or methyl methacrylate (MMA), a small amount of acrylonitrile (AN) and cyclic ketene acetals (CKAs) of different structures. Phosphorous nuclear magnetic resonance allows in-depth chain-end characterization and gives crucial insights into the nature of the copolymer terminal sequences and the living chain fractions. By using a small library of P(OEGMA-co-AN-co-CKA) and P(MMA-co-AN-co-CKA) as macroinitiators, chain extensions with styrene are performed to furnish (amphiphilic) block copolymers comprising a degradable segment. <boxed-text content-type="graphic" position="anchor"> <graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="urn:x-wiley:10221352:media:marc201300809:marc201300809-abs-0001">image</graphic

• 出版日期2014-2