Alcohol use disorder and cognitive impairment in old age patients: A 6 months follow-up study in an outpatient unit in Barcelona

作者：Ros Cucurull Elena; Felipe Palma Alvarez Raul; Cardona Rubira Cristina; Garcia Raboso Elena; Jacas Carlos; Grau Lopez Lara; Carlos Abad Alfonso; Rodriguez Cintas Laia; Ros Montalban Salvador; Casas Miguel; Antoni Ramos Quiroga Josep; Roncero Carlos

来源：Psychiatry Research, 2018, 261: 361-366.

DOI：10.1016/j.psychres.2017.12.069

• Alcohol use
• Cognitive impairment
• Old adults
• Executive functions
• Neuropsychology

There has been little research about deleterious effects, including cognitive impairment, related to hazardous long-term alcohol use in old adults. This study aims to assess cognitive decline in old patients with alcohol use disorder and changes in cognitive state at 6 months follow-up, achieving or not abstinence. A six-month followup study was conducted in an outpatient center in Barcelona on a sample of old adults (>= 65 years old) who had hazardous alcohol use. The sample was compared with healthy volunteers adjusted for age, sex and years of education. A neuropsychological protocol was performed at baseline and after 6 months follow-up covering four cognitive domains: attention, visuospatial abilities, memory and executive functions. Several domains were significant impaired at baseline: visual immediate and delayed recall, working memory, immediate verbal learning, total words learned, set switching and sustained attention. At 6 months reassessment, alcohol abstinence was achieved in 93.5% of patients and it was detected a trend towards improvement in direct mean scores of all cognitive areas, although it was not significant. The current study points out a cognitive impairment in many areas secondary to alcohol long-term hazardous use in old adults. A trend towards cognitive improvement after recovery was detected in most patients.

• 出版日期2018-3