Non-tuberculous mycobacteria in China

作者：Li Weimin; Jiang Guanglu; Liu Zhihui; Hao Huakun; Chai Liquan; Tian Miao; Zhang Xuxia; Niu Tiangui; Petrini Bjorn^*; Li Chuanyou

来源：Scandinavian Journal of Infectious Diseases, 2007, 39(2): 138-141.

DOI：10.1080/00365540600951234

Infection with non-tuberculous mycobacteria (NTM) is relatively rare in areas that are high-endemic for tuberculosis. We identified 126 strains of NTM in respiratory specimens collected by the Chinese Nationwide Survey in 2000, the Beijing Tuberculosis and Thoracic Tumour Institution, and the Guangzhou Thoracic Hospital. Species diagnosis was attained by sequencing of 16S-rDNA complemented by phenotypic characterization when necessary. Mycobacterium avium-intracellulare-complex - well known as a potential pulmonary pathogen - was diagnosed in all 3 surveys. Potentially pathogenic rapid growing strains of M. abscessus, M. chelonae and M. fortuitum were also detected. Moreover, species non-pathogenic in the airways such as M. nonchromogenicum, M. terrae and M. gordonae were encountered. Also, single strains of rare NTM species were isolated. Thus, several potentially pathogenic species of NTM were isolated from pulmonary specimens in China, and molecular techniques made possible exact species diagnosis.

• 出版日期2007
• 单位中国农业大学