An Intervention Target for Myocardial Fibrosis: Autophagy

作者:Lu Chunmiao; Yang Yusong; Zhu Yaping; Lv Shichao; Zhang Junping
来源:Biomed Research International, 2018, 2018: 6215916.
DOI:10.1155/2018/6215916

摘要

Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine.