Atropisomeric bisoxazoline ligands with a bridge across the 5,5 '-position of biphenyl for asymmetric catalysis

作者：Wang, Feijun; Zhang, Yong Jian; Wei, Hao; Zhang, Jiaming; Zhang, Wanbin^*

来源：Tetrahedron Letters, 2007, 48(23): 4083-4086.

DOI：10.1016/j.tetlet.2007.04.007

A new family of atropisomeric bisoxazoline ligands 2 with a bridge across the 5,5'-position of biphenyl has been developed. The axial chirality of this type of ligands can be retained by macro-ring strain produced by 5,5'-linkage of biphenyls even without 6,6'-substituents on biphenyls. The Pd(II)-2d complex as catalyst showed high catalytic activity and enantioselectivity for asymmetric Wacker-type cyclization of allylphenols.

• 出版日期2007-6-4
• 单位上海交通大学