摘要
The aqueous reaction of arylidene pyruvic acids (APAs) with arylamines or urea under refluxing conditions leading to the formation of 3-(amino)-5-aryl-furan-2(5H)-one, without catalyst, is described. Also (E)-4-(4-chlorophenyl)-2-oxobut-3-enoic acid reacts with 1,2-phenylenediamine to form (E)-3-(4-chlorostyryl) quinoxalin-2(1H)-one under the same conditions. Excellent yields were observed after filtration of the product and washing with brine solution.
- 出版日期2013-4-15