Post-marketing Surveillance Systems for Psychoactive Prescription Drug Abuse

作者：Nordmann Sandra; Frauger Elisabeth; Pauly Vanessa; Rouby Frank; Mallaret Michel; Micallef Joelle; Thirion Xavier^*

来源：Therapie, 2011, 66(3): 263-272.

DOI：10.2515/therapie/2011045

• pharmacoepidemiology
• postmarketing surveillance
• prescription study
• psychoactive medications
• substance related disorders

Post-marketing Surveillance Systems for Psychoactive Prescription Drug Abuse. Drugs affecting the central nervous system form a unique group of products for surveillance because they could be misused, abused or diverted. Considering the characteristics of this behaviour that is often concealed, specific post-marketing surveillance systems have been developed to monitor abuse of prescription drugs in some countries.
The purpose of this review is to list and to describe post-marketing surveillance systems, according their methodology, in France and in foreign countries.
These programs are based on adverse effect notifications, medical or legal consequences of abuse, general or specific population-based survey, professional networks or medication databases. Some programs use simultaneously several information sources.
In conclusion, the multifaceted nature, the diversity and the inventiveness of post-marketing surveillance systems reflects the complexity of the abuse issue.

• 出版日期2011-6