A division of labor: asymmetric roles for GPCR subunits in receptor dimers

作者:Zylbergold Peter*; Hebert Terence E
来源:Nature Chemical Biology, 2009, 5(9): 608-609.
DOI:10.1038/nchembio0909-608

摘要

The functional architecture of dimeric or oligomeric GPCR signaling remains incompletely understood. Using a clever combination of receptor-G protein fusions and various receptor mutations, new research provides a glimpse into how oligomers might be arranged with respect to the G proteins they interact with.

  • 出版日期2009-9