A novel electrochemical sensor for glucose detection based on Ag@ZIF-67 nanocomposite

作者：Meng, Wei; Wen, Yuanyuan; Dai, Lei^*; He, Zhangxing; Wang, Ling^*

来源：Sensors and Actuators B: Chemical , 2018, 260: 852-860.

DOI：10.1016/j.snb.2018.01.109

• ZIF-67
• Ag nanoparticles
• Non-enzymatic electrode
• Gluco seensor

In this paper, we demonstrated the first application of a Co-based porous metal-organic framework (MOF) ZIF-67 as the glucose electrochemical sensor. The ZIF-67 modified glassy carbon electrode (GCE) showed an excellent catalytic activity towards glucose oxidation. Meanwhile, to improve the electrocatalytic performance of the modified electrode, a novel Ag@ZIF-67 nanocomposite was fabricated through as equential deposition-reduction method. The Ag@ZIF-67/GCE exhibited an enhanced catalytic activity towards glucose oxidation. The electrocatalytic performance of Ag@ZIF-67 with different Ag loadings was investigated, and the results indicated that with the Ag contents increasing from 0% to 0.5%, the response time of the modified electrode was shorten by more than two times, and the sensitivity was increased by two times and a half. The Ag-0.5%@ZIF-67GCE exhibited excellent electrocatalytic performances in the glucose concentration range of 2-1000 mu M, including a high sensitivity of 0.379 mu A mu M-1 cm(-2), a low detection limit of 0.66 mu M (S/N = 3) as well as good selectivity and stability.

• 出版日期2018-5-1
• 单位中国科学技术大学