A stereocontrolled synthesis of the hydrophobic moiety of rhamnolipids

作者：Menhour Boudjema; Mayon Patrick; Ple Karen; Bouquillon Sandrine; Dorey Stephan; Clement Christophe; Deleu Magali; Haudrechy Arnaud^*

来源：Tetrahedron Letters, 2015, 56(9): 1159-1161.

DOI：10.1016/j.tetlet.2015.01.091

• Rhamnolipids
• Enzymatic resolution
• Mitsunobu reaction
• Cross metathesis reaction

A new approach toward the synthesis of the hydrophobic moiety of rhamnolipid derivatives has been developed, involving two key cross-metatheses and an unusual Mitsunobu reaction. Small structural variations of the side chains should enable a better understanding of the role of the lipid moiety in immunostimulatory and plant defense eliciting properties.

• 出版日期2015-2-25