Accelerating the search for the missing proteins in the human proteome

Baker Mark S; Ahn Seong Beom; Mohamedali Abidali; Islam Mohammad T; Cantor David; Verhaert Peter D; Fanayan Susan; Sharma Samridhi; Nice Edouard C; Connor Mark; Ranganathan Shoba

doi:10.1038/ncomms14271

登录

免费注册

赞收藏引用

科研之友

微信

新浪微博

Facebook

分享链接

Accelerating the search for the missing proteins in the human proteome

作者：Baker Mark S; Ahn Seong Beom; Mohamedali Abidali; Islam Mohammad T; Cantor David; Verhaert Peter D; Fanayan Susan; Sharma Samridhi; Nice Edouard C; Connor Mark; Ranganathan Shoba

来源：Nature Communications, 2017, 8(1): 14271.

DOI：10.1038/ncomms14271

摘要

The Human Proteome Project (HPP) aims to discover high-stringency data for all proteins encoded by the human genome. Currently, similar to 18% of the proteins in the human proteome (the missing proteins) do not have high-stringency evidence (for example, mass spectrometry) confirming their existence, while much additional information is available about many of these missing proteins. Here, we present MissingProteinPedia as a community resource to accelerate the discovery and understanding of these missing proteins.