Bladder capacity in kidney transplant patients with end-stage renal disease

作者：Song Miho; Park Junsoo; Kim Young Hoon; Han Duck Jong; Song Sang Hoon; Choo Myung Soo; Hong Bumsik^*

来源：International Urology and Nephrology, 2015, 47(1): 101-106.

DOI：10.1007/s11255-014-0848-1

• End-stage renal disease
• Bladder capacity
• Kidney transplantation
• Lower urinary tract symptom

This study evaluated the clinical factors that influence bladder capacity and lower urinary tract dysLUTD) following kidney transplantation (KT) in end-stage renal disease (ESRD) patients.
Data were analyzed in ESRD patients who underwent KT between January 2011 and January 2013. The analyzed pre-KT parameters include bladder capacity, vesicoureteral reflux (VUR), postvoid residual urine (PVR), micturition frequency, and voiding volume. Associations between pre-KT parameters, small bladder capacity (< 100 cc), and parameters that influence the development of LUTD were also evaluated. LUTD after KT was defined as voiding symptoms that lasted > 1 month and required specific treatment.
In total, 622 ESRD patients required KT. The mean age and dialysis duration were 43.9 +/- A 11.2 years and 59.4 +/- A 60.7 months. The mean bladder capacity before KT was 300.1 +/- A 149.8 mL, and 14 % of patients were diagnosed with small bladder capacity. VUR and PVR were observed in 110 (17.5 %) and 83 (13.6 %) patients. Factors associated with small bladder capacity included long-term dialysis, presence of VUR, and PVR (p < 0.001, p = 0.004, p = 0.003). After KT, 31 patients (4.9 %) needed treatment due to LUTD. Factors associated with the development of LUTD included age, VUR, and PVR (p = 0.001 p = 0.034, p < 0.001). Bladder capacity did not affect LUTD after KT.
ESRD patients on long-term dialysis will likely have small bladder capacity and VUR; however, bladder capacity itself is not related to the occurrence of LUTD after KT.

• 出版日期2015-1