Association Between Obesity, Abdominal Obesity, and Adiposity and the Prevalence of Atopic Dermatitis in Young Korean Adults: the Korea National Health and Nutrition Examination Survey 2008-2010

作者：Lee Ji Hyun; Do Han Kyung; Jung Han Mi; Youn Young Hoon; Lee Jun Young; Park Yong Gyu; Lee Seung Hwan^*; Park Young Min^*

来源：Allergy Asthma & Immunology Research, 2016, 8(2): 107-114.

DOI：10.4168/aair.2016.8.2.107

• Atopic dermatitis
• obesity
• body mass index
• waist circumference
• body fat
• prevalence

Purpose: Whether obesity is a risk factor for atopic dermatitis (AD) remains unclear. The aim of the present study was to investigate the association between obesity and AD in Korean young adults. Methods: We included nationally representative data of 5,202 Korean adults aged 19-40 years, obtained from the cross-sectional Korea National Health and Nutrition Examination Survey 2008-2010.. Results: Single (unmarried) status was more frequently observed in AD patients (male, [P=0.0002] and female, [P<0.0001]). AD prevalence exhibited a U-shape trend in relation to body mass index (BMI), waist circumference (WC), and total body fat (BF) percentage, especially in young adult women. Women with BMI >= 25 kg/m(2), WC >= 80 cm, and highest quartile (Q4) of total BF percentage had the highest prevalence of AD. The odds ratio (OR) for participants with both BMI >= 25 kg/m(2) and WC >= 80 cm was 3.29 (95% confidence interval [CI] 1.71-3.55); therefore, having both general and abdominal obesity was considered a prominent risk factor for AD in young women. After adjustment for confounding factors, including age, smoking, alcohol drinking, exercise, vitamin D, income level, and single status, high BMI (>= 30 kg/m(2)) (OR=4.08, 95% Cl: 1.53-10.93), high WC (>= 80 cm) (OR=2.05, 95% Cl: 1.07-3.94), and high BF percentage (Q4) (OR=2.10, 95% CI: 1.24-3.57) were shown to be significantly associated with AD in young adult women. Conclusions: In this large-scale nation-wide study of Korean adults, obesity was positively related to the presence of AD in women. Our findings suggest that weight management may help prevent AD.

• 出版日期2016-3