A new method for pyrrole peri-annulation: synthesis of 1H-1,5,7-triazacyclopenta[c,d]phenalenes from 1H-perimidines

作者：Aksenov Alexander V^*; Lyakhovnenko Alexander S; Andrienko Anna V; Levina Irina I

来源：Tetrahedron Letters, 2010, 51(18): 2406-2408.

DOI：10.1016/j.tetlet.2010.02.129

• Schmidt reaction
• Polyphosphoric acid
• peri-Annulation
• Perimidines
• 1H-1,5,7-Triazacyclopenta[c,d]phenalenes

New methods for the synthesis of 1H-1,5,7-triazacyclopenta[c,d]phenalenes have been developed based on a sequence involving Schmidt reaction of keto-perimidines and acylation of the intermediate amides with 1,3,5-triazines or carboxylic acids. The same synthetic sequence starting from the corresponding alkylperimidine includes acylation with acetic acid as the first step.

• 出版日期2010-5-5