科研之友
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摘要
The aim of this study was to prepare and characterize permethrin-loaded lipid core nanocapsules (P-LNC) in order to produce a long last insect repellent spray formulation for clothes. P-LNC were prepared by self-assembling in aqueous solution showing a mean diameter of 201 +/- 4 nm with a monomodal distribution, a permethrin content of 4.6 +/- 0.1 mg/mL and zeta potential of -16.7 +/- 4 mV. P-LNC (0.46%), as well as the commercial product (0.46%) and the hydroalcoholic solution (0.50%) of permethrin were separately sprayed onto cotton or polyester, followed by successive washes of the fabric. The results showed that the fabrics treated with P-LNC are more resistant than other solutions in terms of remaining permethrin content. After twenty washes, the cotton treated with P-LNC, presented a concentration of 566 +/- 27 mg/m(2) of impregnated permethrin, while for the treatment with the substance hydroalcoholic solution and with the commercial product the concentrations values were of 340 +/- 7 mg/m(2) and 224 +/- 74 mg/m(2), respectively. When the test was performed using polyester, this fiber was less adhesive than cotton, resulting in a final concentration of permethrin (after 20 washes) of 81 +/- 10 mg/m(2) for P-LNC suspension, 94 +/- 8 mg/m(2) for the substance hydroalcoolic solution and 22 +/- 3 mg/m(2) for the commercial product. After impregnating cotton with the formulations and submitting to a temperature of 200 degrees C, the P-LNC also demonstrated higher adherence compared to the other formulations (407 +/- 67 mg/m(2) for P-LNC, 236 +/- 72 mg/m(2) for the substance hydroalcoholic solution and 158 +/- 62 mg/m(2) for commercial product). These results showed that the repellent spray composed of P-LNC developed in this work is a promising and innovative product for the individual protection against insects, useful for impregnation onto cotton garments.
- 出版日期2016-2
