An algebraic approach to proving the global stability of a class of epidemic models

作者:Li, Jianquan*; Xiao, Yanni; Zhang, Fengqin; Yang, Yali
来源:Nonlinear Analysis: Real World Applications , 2012, 13(5): 2006-2016.
DOI:10.1016/j.nonrwa.2011.12.022

摘要

The global stability of an autonomous differential equation system is an important issue for ecological, epidemiological and virus dynamical models. By means of the direct Lyapunov method and the LaSalle's Invariance Principle, an algebraic approach to proving the global stability is presented in this paper. This approach gives a logic and possibly programming method on how to choose coefficients a(i) based on the classic Lyapunov function of the form Sigma(n)(i=1) a(i)(x(i) - x*(i) - x*(i) In x(i)/x*(i)) such that the derivative of the Lyapunov function is negative definite or semidefinite. As an application, the global stability of an SVS-SEIR epidemic model with vaccination and the latent stage is examined. The generality of the approach is also shown by discussing certain cases.