Designing Inorganic Light-Protective Skin Nanotechnology Products

作者：Popov Alexey P^*; Zvyagin Andrei V; Lademann Juergen; Roberts Michael S; Sanchez Washington; Priezzhev Alexander V; Myllyla Risto

来源：Journal of Biomedical Nanotechnology, 2010, 6(5): 432-451.

DOI：10.1166/jbn.2010.1144

• Nanoparticles
• TiO(2)
• ZnO
• Sunscreen
• UV
• Penetration
• Toxicity
• Skin
• Monte Carlo Simulation
• Mie Theory
• Scattering
• Absorption
• Stratum Corneum

In this review, we discuss the use of inorganic nanoparticles, mainly zinc oxide (ZnO) and titanium dioxide (TiO(2)), for sunscreen applications considering their intrinsic physical properties and the Mie theory. These properties cause, from one side, attenuation of the ultraviolet light by absorption and scattering (dependent on a particle size), which is the purpose sunscreens are designed for, and formation of free radicals (i.e., phototoxicity) during this process-from the other. Particle penetration into skin is also an important issue addressed in this review due to possible adverse effects associated with interaction between nanoparticles and skin living cells.

• 出版日期2010-10