Determination of T-2 and HT-2 Toxins in Traditional Chinese Medicine Marketed in China by LC-ELSD after Sample Clean-Up by Two Solid-Phase Extractions

作者：Tan, Yinfeng; Kuang, Ying; Zhao, Runhuai; Chen, Bo; Wu, Jianwei^*

来源：Chromatographia, 2011, 73(3-4): 407-410.

DOI：10.1007/s10337-010-1890-5

• Column liquid chromatography
• LC-ESI-MS-MS
• T-2 toxin
• HT-2 toxin
• Traditional chinese medicine
• Functional food

LC-ELSD has been applied for the determination of T-2 and HT-2 toxins in Traditional Chinese Medicine (TCM) marketed in China. For sample preparation, two clean-up procedures were developed using Florisil and MycoSep227 for solid-phase extraction. Limits of detection (10 ng g(-1)) as well as recoveries are described. A total of 138 samples of 46 commercially available TCM samples was analyzed; only one sample was determined to contain T-2 at a level of 64.0 ng g(-1), and positive results were further confirmed by LC-ESI-MS-MS.

• 出版日期2011-2
• 单位中国医学科学院北京协和医院; 河北医科大学; 海南医学院; 北京协和医学院