aMAGEing New Players Enter the RING to Promote Ubiquitylation

作者：Espantman Kristen C; O'Shea Clodagh C^*

来源：Molecular Cell, 2010, 39(6): 835-837.

DOI：10.1016/j.molcel.2010.09.006

The MAGE proteins are best known as curious tumor-specific antigens. However, Doyle et al. (2010) reveal that MAGE proteins interact with RING proteins to promote ubiquitylation which provides important new insights into the physiological and pathological functions of this enigmatic family of proteins.

• 出版日期2010-9-24