Nickel-Catalyzed C-P Cross-Coupling of Arylboronic Acids with P(O)H Compounds

作者:Hu Gaobo; Chen Weizhu; Fu Tingting; Peng Zhimin; Qiao Hongwei; Gao Yuxing*; Zhao Yufen
来源:Organic Letters, 2013, 15(20): 5362-5365.
DOI:10.1021/ol402672e

摘要

A novel and efficient Ni-catalyzed coupling of a wide range of arylboronic acids with H-phosphites, H-phosphinate esters, and H-phosphine oxides has been developed, providing a general and powerful tool for the synthesis of various aryl-phosphorus compounds, especially for valuable triarylphosphine oxides, in good to excellent yield. This protocol is the first Ni-catalyzed C-P bond-forming reaction between arylboronic acids and P(O)H compounds.