Alsmaphorazines C-E, indole alkaloids from Alstonia pneumatophora

作者：Koyama Koichiro; Hirasawa Yusuke; Nugroho Alfarius E; Kaneda Toshio; Hoe Teh Chin; Chan Kit Lam; Morita Hiroshi^*

来源：Tetrahedron, 2012, 68(5): 1502-1506.

DOI：10.1016/j.tet.2011.12.014

• Indole alkaloids
• Alston ia pneumatophora
• Alsmaphorazines C-E
• Modified Masher%26apos
• s method

Three novel indole alkaloids, alsmaphorazines C (1)-E (3), were isolated from the leaves of Alstonia pneumatophora (Apocynaceae) and their structures were determined on the basis of the 2D NMR and MS spectral analyses. The absolute configurations of 1 and 3 were elucidated by applying a modified Mosher%26apos;s method and CD spectral analysis. These alkaloids possessed novel ring skeletons containing an octahydropyrrolo[2,3-blpyrrole unit.

• 出版日期2012-2-4