A Multiple-Stimulus-Responsive Biomimetic Assembly Based on a Polyisocyanopeptide and Conjugated Polymer

作者：Meng, Fanfan; Xing, Chengfen^*; Yuan, Hongbo; Fan, Yibing; Chai, Ran; Zhan, Yong

来源：Chemistry-An Asian Journal, 2017, 12(22): 2962-2966.

DOI：10.1002/asia.201701280

• biomimetic synthesis
• conjugation
• peptides
• polymers
• supramolecular chemistry

An assembly was fabricated and was revealed to be a multiple-stimulus-responsive biomimetic hybrid polymer architecture. It was constructed by the hydrophobic interactions between a conjugated polyfluorene that contained 2,1,3-benzothiadiazole units (PFBT) and a tri(ethylene glycol)-functionalized polyisocyanopeptide (3OEG-PIC). The introduction of PFBT to the polyisocyanopeptide (PIC) network allowed for the incorporation of responsiveness to multiple stimuli including temperature, CO2, carbonic anhydrase, and nonlinear mechanics, which mimics natural processes and interactions. Furthermore, the light-harvesting and signal amplification characteristics of PFBT endowed the supramolecular assembly with the essential function of fluorescence monitoring for biological processes.

• 出版日期2017-11-16
• 单位河北工业大学