Agreement between Pentacam and optical coherence tomography in the assessment of iridocorneal angle width in a large healthy population

作者：Fernandez Vigo J I^*; De Pablo Gomez de Liano L; Almorin Fernandez Vigo I; Fernandez Vigo C^*; Macarro Merino A; Garcia Feijoo J; Fernandez Vigo J A^*

来源：Journal Francais d Ophtalmologie, 2018, 41(1): 14-20.

DOI：10.1016/j.jfo.2017.07.003

• Anterior-chamber angle
• Iridocorneal angle
• Anterior segment optical coherence tomography
• Glaucoma
• Scheimpflug device

Purpose. To analyze the agreement between Pentacam and optical coherence tomography (OCT) in the assessment of trabecular-iris angle (TIA) width in a large population of normal subjects.
Methods. A cross-sectional study was performed in 989 right eyes of 989 healthy subjects. The trabecular-iris angle (TIA) was measured in the temporal and nasal quadrants using the Pentacam (Oculus, Wetzlar, Germany), a device based on Scheimpflug technology and RTVue 100 OCT (Optovue, Fremont, CA, USA). Intraclass correlation coefficients (ICC) and Bland Altman plots were used to evaluate agreement between these devices.
Results. Mean age was 49.1 +/- 15.2 years (18-84); 61% were women and spherical error range was 14 to 8.25. TIA could be measured by OCT in 94.9% and 94.1% in the temporal and nasal quadrants, with a mean value of 35.8 +/- 13.2 degrees (2.5-78.7) and 35.7 +/- 12.9 degrees (2.2-76.8) respectively. TIA was able to be measured by Pentacam in 95.2% and 95% in the temporal and nasal quadrants and means were 35.7 +/- 7.3 degrees (11-74.2) and 36.4 +/- 8.2 degrees (14.5-64) respectively. An ICC of 0.378 (95% confidence interval [CI], 0.322-0.431) and 0.589 (95% CI 0.546-0.629) for the temporal and nasal quadrants was obtained, showing moderate agreement between the devices. Bland-Altman plots revealed that, compared with OCT, Pentacam tends to overestimate measurements in narrow angles and underestimate these in open angles.
Conclusions. Agreement between OCT and Pentacam was mediocre, indicating the two devices are not interchangeable when used to measure angle width.

• 出版日期2018-1