An Improved Convergent Strategy for the Synthesis of Oligoprenols

作者:Yu, Xiong-Jie; Zhang, Hao; Xiong, Fang-Jun; Chen, Xu-Xiang; Chen, Fen-Er*
来源:Helvetica Chimica Acta, 2008, 91(10): 1967-1974.
DOI:10.1002/hlca.200890211

摘要

A practical and highly regio- and stereoselective synthesis of oligoprenols starting from commercially available geraniol is described, The convergent synthetic strategy features the iterative allyl-allyl coupling of monomers easily derived from geraniol that contain one reacting terminal functional group and the repetitive reductive elimination of the p-toluenesulfonyl (Ts) groups.

全文