Determination of Sinomenine in Cubosome Nanoparticles by HPLC Technique

作者：Zhou, Yanfang; Guo, Chunlian; Chen, Hongying; Zhang, Yudai; Peng, Xinsheng^*; Zhu, Ping

来源：Journal of Analytical Methods in Chemistry, 2015, 2015: 931687.

DOI：10.1155/2015/931687

• ARTHRITIS

We applied HPLC technique to quantitatively analyze sinomenine in cubosome nanoparticles. The chromatographic method was performed by using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0.1%) with a flow rate of 1 mL/min; the detection wavelength was at 265 nm. Sinomenine can be successfully separated with good linearity (the regression equation is A = 10835C + 1058; R-2 = 1.0) and perfect recovery (102.2%). The chromatograph technique was proper for quality control of sinomenine in cubosome nanoparticles.

• 出版日期2015
• 单位广东省人民医院; 广东医科大学; 广东省心血管病研究所