科研之友
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摘要
The asymmetric reductive amination of aryl-ketones bearing various boron-functionalities (acid, ester or potassium trifluoroborates) was investigated employing enantiocomplementary omega-transaminases as catalysts. Under the optimized conditions, high conversions (up to 94%) and excellent ee%26apos;s (up to %26gt;99%) were obtained providing access to both (R)- and (S)-configured amino-aryl boronates under mild reaction conditions.
- 出版日期2013-12-15
