A new chromone glycoside from Rhododendron spinuliferum

作者：Chen, Gang; Jin, Hui Zi^*; Li, Xue Feng; Zhang, Qi; Shen, Yun Heng; Yan, Shi Kai; Zhang, Wei Dong

来源：Archives of Pharmacal Research, 2008, 31(8): 970-972.

DOI：10.1007/s12272-001-1253-y

• Rhododendron spinuliferum
• chromone
• 3,5,7-trihydroxylchromone-3-O-alpha-L-arabinopyranoside
• nitric oxide (NO) production

A new chromone glycoside, 3,5,7-trihydroxylchromone-3-O-alpha-L-arabinopyranoside (1), together with quercetin (2), (+)-catechin (3), (-)-epi-catechin (4) were isolated from the aerial parts of Rhododendron spinulferum. The structure of 1 was elucidated on the basis of spectroscopic and 2D-NMR spectral analysis. In addition, 1 exhibited mild inhibitory effect on NO production in LPS-stimulated RAW264.7 cells.

• 出版日期2008-8
• 单位中国人民解放军第二军医大学; 江西中医药大学; 南京工业大学; 上海交通大学