Age-related changes in light microscopy with Sirius red technique in rat Achilles tendon

作者：Oktem Hale^*; Calguner Engin; Erdogan Deniz; Elmas Cigdem; Gozi Rabet; Kadioglu Dural; Goktas Guleser

来源：Joint Diseases and Related Surgery, 2010, 21(1): 50-55.

• Achilles tendon/injuries
• age-related changes
• rats
• Sirius red

Objectives: In this study, age-related morphological changes in intact rat Achilles tendon was investigated
Materials and methods: Thirty Wistar albino rats of 2-3 weeks, six months and 12 months old,groups 10 animal in each group were examined with Sirius red light microscobic staining.
Results: The Sirius red light microscobic staining revealed that red stained collagen fibers have a decreased waviness with more rounded appearence of tenocyte extracellular matrix along a increased vascularity and the number of tenocytes decreased with age was statistically meaningfull
Conclusion: The possible causes of the spontaneously Achilles tendon rupture in adult ages group was investigated with Sirius red light microscopic technique In this age group, initiation of the degenerative changes are decreasing the elasticity thus function of this tendon

• 出版日期2010