Does intramuscular thermal feedback modulate eccrine sweating in exercising humans?

作者：Todd G; Gordon C J; Groeller H; Taylor N A S^*

来源：Acta Physiologica, 2014, 212(1): 86-96.

DOI：10.1111/apha.12327

• core temperature
• exercise
• muscle temperature
• sweating
• thermoregulation

AimFew investigators have considered the possibility that skeletal muscles might contain thermosensitive elements capable of modifying thermoeffector responses. In this experiment, the temporal relationships between dynamic changes in deep-body and intramuscular temperatures and eccrine sweat secretion were explored during rhythmical and reproducible variations in heat production. %26lt;br%26gt;MethodsEight subjects performed semi-recumbent cycling (25 degrees C) at a constant load to first establish whole-body thermal and sudomotor steady states (35min), followed by a 24-min block of sinusoidal workload variations (three, 8-min periods) and then returning to steady-state cycling (20min). Individual oesophageal, mean skin and intramuscular (vastus lateralis) temperatures were independently cross-correlated with simultaneously measured forehead sweat rates to evaluate the possible thermal modulation of sudomotor activity. %26lt;br%26gt;ResultsBoth intramuscular and oesophageal temperatures showed strong correlations with sinusoidal variations in sweating with respective maximal cross-correlation coefficients of 0.807 (0.044) and 0.845 (+/- 0.035), but these were not different (P=0.40). However, the phase delay between intramuscular temperature changes and sweat secretion was significantly shorter than the delay between oesophageal temperature and sweating [25.6s (+/- 12.6) vs. 46.9s (+/- 11.3); P=0.03]. %26lt;br%26gt;ConclusionThe temporal coupling of eccrine sweating to intramuscular temperature, combined with a shorter phase delay, was consistent with the presence of thermosensitive elements within skeletal muscles that appear to participate in the modulation of thermal sweating.

• 出版日期2014-9