Antidiabetic dimeric guianolides and a lignan glycoside from Lactuca indica

作者:Hou CC; Lin SJ; Cheng JT; Hsu FL*
来源:Journal of Natural Products, 2003, 66(5): 625-629.
DOI:10.1021/np0205349

摘要

Three novel sesquiterpene lactones, lactucain A (1), B (2), and C (3), and a new furofuran lignan, lactucaside (4), were isolated from Lactuca indica along with nine known compounds, 11b,13-dihydrolactucin, cichoriosides B, quercetin, quercetin 3-O-glucoside, rutin, apigenin, luteolin, luteolin 7-O-glucuronide, and chlorogenic acid. Among these compounds, latucain C (3) and lactucaside (4) showed significant antidiabetic activity.

  • 出版日期2003-5