A novel BNCT irradiation system with an on-line monitor using Li-7(P,N)Be-7 near threshold neutrons

作者：Kobayashi Tooru; Bengua Gerard^*; Tanaka Kenichi; Hayashizaki Noriyosu; Katabuchi Tatsuya; Hattori Toshiyuki; Aritomi Masanori

来源：Radiation Measurements, 2011, 46(12): 2000-2002.

DOI：10.1016/j.radmeas.2011.08.024

• Accelerator
• Near-threshold
• Li-7(p,n)Be-7 reaction
• Direct neutron usage
• Liquid lithium target

A neutron irradiation system for boron neutron capture therapy using accelerators with an online dose monitoring system was studied for the possible practical implementation of hospital-based BNCT. For this purpose the neutrons produced by the near threshold Li-7(p,n)Be-7 reaction, i.e. an incident proton energy of around 1.90 MeV, have suitable properties. Such as the maximum energy below 100 key and mostly forward-directed. A good candidate material to shield gamma rays from the Li-target was Lead and the suitable boron-dose enhancer was polyethylene. The optimum physical dimensions and configuration of the irradiation system was determined using the concept of treatbale protocol depth as figures of merit. For the online monitor system, the single photon emission computed tomography using prompt gamma-ray was studied to provide an ideal dose estimation system. A neutron producing target system with a liquid lithium jet flow of about 30 m/s at a thickness of 1 mm and a cross-sectional area of 50 mm x 50 mm is proposed.

• 出版日期2011-12