MAPPING OF THE MOUSE BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE GENE (GNT-1) TO CHROMOSOME-1 BY RESTRICTION FRAGMENT LENGTH VARIATIONS

作者：SATO H^*; SAKAI Y; KOIWAI O; WATANABE T

来源：Biochemical Genetics, 1992, 30(7-8): 347-352.

DOI：10.1007/BF00569325

• CHROMOSOME MAPPING
• MOUSE BILIRUBIN UDP-GLUCURONOSYLTRANSFERASE

Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test using Elo and En-1 as marker genes, the bilirubin UDPGT gene was mapped at position 37 on chromosome 1. Bilirubin and phenol UDPGTs have been suggested to be expressed by a single gene by alternative splicing in human and rat The mouse bilirubin UDPGT gene was named Gnt-1.

• 出版日期1992-8