A New and Facile Synthesis of Quinazoline-2,4(1H,3H)-diones

作者：Li Jiarong^*; Chen Xian; Shi Daxin; Ma Shuling; Li Qing; Zhang Qi; Tang Jianhong

来源：Organic Letters, 2009, 11(6): 1193-1196.

DOI：10.1021/ol900093h

A new and facile preparation of quinazoline-2,4(1H,3H)-diones was first reported which was the condensation of aromatic o-aminonitriles with DMF or N,N-diethylformamide in the presence of ZnCl(2) (0.5-10 mol %) at 190-200 degrees C in the sealed reactor.

• 出版日期2009-3-19
• 单位北京理工大学