Stress and sexual reproduction affect the dynamics of the wheat pathogen effector AvrStb6 and strobilurin resistance

作者：Kema Gerrit H J; Gohari Amir Mirzadi; Aouini Lamia; Gibriel Hesham A Y; Ware Sarah B; van den Bosch Frank; Manning Smith Robbie; Alonso Chavez Vasthi; Helps Joe; Ben M'Barek Sarrah; Mehrabi Rahim; Diaz Trujillo Caucasella; Zamani Elham; Schouten Henk J; van der Lee Theo A J; Waalwijk Cees; de Waard Maarten A; de Wit Pierre J G M; Verstappen Els C P; Thomma Bart P H J; Meijer Harold J G; Seidl Michael F

来源：Nature Genetics, 2018, 50(3): 375-+.

DOI：10.1038/s41588-018-0052-9

Host resistance and fungicide treatments are cornerstones of plant-disease control. Here, we show that these treatments allow sex and modulate parenthood in the fungal wheat pathogen Zymoseptoria tritici. We demonstrate that the Z. triticiwheat interaction complies with the gene-for-gene model by identifying the effector AvrStb6, which is recognized by the wheat resistance protein Stb6. Recognition triggers host resistance, thus implying removal of avirulent strains from pathogen populations. However, Z. tritici crosses on wheat show that sex occurs even with an avirulent parent, and avirulence alleles are thereby retained in subsequent populations. Crossing fungicide-sensitive and fungicide-resistant isolates under fungicide pressure results in a rapid increase in resistance-allele frequency. Isolates under selection always act as male donors, and thus disease control modulates parenthood. Modeling these observations for agricultural and natural environments reveals extended durability of host resistance and rapid emergence of fungicide resistance. Therefore, fungal sex has major implications for disease control.

• 出版日期2018-3