Novel metabolites from the roots of Cadaba natalensis

作者：Monjane J A; Uamusse A; Sterner O^*

来源：Phytochemistry Letters, 2016, 16: 283-286.

DOI：10.1016/j.phytol.2016.05.009

• Cadaba natalensis
• Diazacyclododecanedione
• Oxazolidinone
• Isoquiniline alkaloids
• Isolation
• Structure elucidation

From an extract of the roots of Cadaba natalensis Sond. the novel macrocyclic dibenzo-diazacyclodo-decanedione 1 was isolated together with (S)-2-ethyl-2-methyloxazolidin-5-one (2a). In addition, the five known compounds were obtained. Of these, (R)-5-ethyl-5-methyloxazolidin-2-one (3) is reported as a natural product for the first time. The structures of the isolated compounds were elucidated by analysis of the spectral data, 1D NMR (H-1, C-13, and DEPT), 2D NMR (COSY, HMQC, HMBC, and NOESY), and HRESIMS, as well as by the comparison with previously reported data.

• 出版日期2016-6