A new Bayesian model applied to cytogenetic partial body irradiation estimation

作者:Higueras Manuel*; Puig Pedro; Ain**ury Elizabeth A; Vinnikov Volodymyr A; Rothkamm Kai
来源:Radiation Protection Dosimetry, 2016, 168(3): 330-336.
DOI:10.1093/rpd/ncv356

摘要

A new zero-inflated Poisson model is introduced for the estimation of partial body irradiation dose and fraction of body irradiated. The Bayes factors are introduced as tools to help determine whether a data set of chromosomal aberrations obtained from a blood sample reflects partial or whole body irradiation. Two examples of simulated cytogenetic radiation exposure data are presented to demonstrate the usefulness of this methodology in cytogenetic biological dosimetry.