Monitoring of hydroxyapatite conversion by luminescence intensity of Eu3+ ions during mineralization of Eu3+-doped beta-Ca2SiO4

作者：Zhang, Yin; Chen, Jie; Li, Yadong^*; Seo, Hyo Jin

来源：Optical Materials, 2014, 37: 525-530.

DOI：10.1016/j.optmat.2014.07.017

• Dicalcium silicate
• Eu3+ ions
• Hydroxyapatite conversion
• Luminescence intensity
• Monitor

beta-Dicalcium silicate (beta-Ca2SiO4) doped with Eu3+ was synthesized by sol-gel method. The luminescence intensity of the mineralization products formed during the hydroxyapatite (Ca-10(PO4)(6)(OH)(2), HA) conversion of Eu3+-doped beta-Ca2SiO4, in 0.25 M K2HPO4 solution, were detected using luminescence spectroscopy. The results indicated that the luminescence intensity of Eu3+ ion gradually depressed with prolonged mineralization time, and it could hardly be detected with the complete transformation from beta-Ca2SiO4:Eu3+ to hydroxyapatite. The change of Eu3+ ionic concentrations in the mineralization products and the final solutions after conversion reaction, were further examined using energy-dispersive X-ray and inductively-coupled plasma mass spectrometry, respectively. This suggested that the process of mineralization can be monitored with the luminescence intensity of Eu3+ ions in the mineralization products. The current study will open up a new and simple in vivo avenue for in situ monitoring hydroxyapatite conversion with a fiber luminescence spectrometer.

• 出版日期2014-11
• 单位苏州大学