科研之友
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摘要
9-(N,N-Dimethyl)-4,7-megastigmedien-3-one (1) was isolated from Pachysandra terminalis and identified by 1D and 2D NMR spectroscopic and mass spectrometric methods. Compound 1 revealed significant anti-metastasis effect on cancer cell migration and invasion through suppressing the expressions of p-PKC zeta and p-integrin beta 1 in human breast cancer cells, and also showed anti-angiogenic activity on human umbilical vein endothelial cells.
- 出版日期2015-3
- 单位天津医科大学
