Acute perioperative disturbances of renal function Strategies for prevention and therapy

作者：Jaschinski U^*; Lichtwarck Aschoff M

来源：Anaesthesist, Der, 2009, 58(8): 829-847.

DOI：10.1007/s00101-009-1592-2

• Causal mechanism
• RIFLE criteria
• Diuretics
• Fluid administration
• Volume therapy

The increasing life expectancy in industrial nations leads to an increase in the number of elderly and aged persons treated in hospital. Increasingly more complex operations are being carried out on this group of patients. Renal dysfunction in the preoperative situation increases morbidity and mortality. Acute kidney injury (AKI) is nearly always part of a multi-organ dysfunction syndrome in critically ill patients. The treatment strategy of the AKI should be oriented to the degree of organ dysfunction. However, the stage of organ dysfunction is mostly unknown so that the therapeutically exploitable interval is often missed. The same therapy is practically always used for all patients: administration of fluids and diuretics often under the premise of"the kidneys must be rinsed". A unified classification of the continuation of kidney function disorders using the RIFLE criteria (risk, injury, failure, loss, endstage kidney disease) can assist recognition of early stages of kidney failure in order to react correspondingly with therapeutic measures and to critically question or optimize the use of conservative treatment strategies.

• 出版日期2009-8