ASSESSMENT OF THE "MICRO-GREENNESS" OF SYNTHESES USING THE GREEN STAR.

作者：Duarte Rita C C^*; Ribeiro Maria Gabriela T C; Machado Adelio A S C

来源：Quimica Nova, 2014, 37(6): 1085-U268.

DOI：10.5935/0100-4042.20140168

• green metrics
• micro-greenness
• reaction greenness improvement
• green chemistry education
• green synthesis

This article reports a study to increase the overall greenness of chemical syntheses for first-year university laboratories. The separate evaluation of the micro-greenness of the three stages of synthesis (reaction, isolation and purification) using the Green Star (GS) was implemented and their respective contribution to overall greenness was investigated for two examples: syntheses of cobalt (III) tris(acetylacetonate) and potassium nitrilosulfonate. Results showed that the post-reaction (work-up) steps are the most problematic for overall greenness. Greenness optimization can be achieved by combining the greenest procedures for each step obtained from different protocols available in the literature.

• 出版日期2014