A propos of glycosyl cations and the mechanism of chemical glycosylation

作者：Bohe Luis; Crich David^*

来源：Comptes Rendus Chimie, 2011, 14(1): 3-16.

DOI：10.1016/j.crci.2010.03.016

• Carbohydrates
• Carbocations
• Glycosylation
• Nucleophilic substitution
• Substituent effects
• Solvent effects
• Diastereoselectivity

A critical overview of the current state of the art regarding the mechanism of chemical glycosylation reactions is presented. Particular emphasis is placed on the glycosyl oxocarbenium ions and the evidence for and against their existence and their intermediacy in glycosylation reactions. The various factors influencing the mechanism of a glycosylation reaction are commented.

• 出版日期2011-1