Hybrid Microgels with Antibacterial Properties

作者：Haentzschel Nadine; Hund Rolf Dieter; Hund Heike; Schrinner Marc; Lueck Christian; Pich Andrij^*

来源：Macromolecular Bioscience, 2009, 9(5): 444-449.

DOI：10.1002/mabi.200800219

• antibacterial properties
• microgel
• silver nanoparticles
• structure

In the present work, we have used aqueous microgels as containers for the deposition of silver nanoparticles (AgNPs). It has been shown that AgNPs can be effectively incorporated in the microgel interior during the in situ reduction of silver ions. Obtained hybrid microgels with variable AgNPs loading (from 1 to 12 wt.-%) have been used as antibacterial agents for two bacteria types. The experimental results indicate that porous microgel structure allows the release of the silver ions from the AgNPs surface into an aqueous phase. This ensures effective reduction in the number of bacterial colonies in test plates and complete bacteria killing. The antibacterial efficiency of the microgel particles increases with AgNPs loading.

• 出版日期2009-5-13
• 单位河北医科大学