ANTIOXIDANT EFFECT OF A FERMENTED POWDER OF LADY JOY BEAN IN PRIMARY RAT HEPATOCYTES

作者:La Marca Margherita; Pucci Laura; Bollini Roberto; Russo Rossella; Sparvoli Francesca; Gabriele Morena; Longo Vincenzo
来源:Cellular and Molecular Biology Letters, 2015, 20(1): 102-116.
DOI:10.1515/cmble-2015-0007

摘要

<jats:title>Abstract</jats:title><jats:p>The role and beneficial effects of plant and food extracts against various diseases induced by oxidative stress have received much attention in recent years. Legumes are rich in bioactive compounds, and some studies suggest a correlation between their consumption and a reduced incidence of diseases. Primary cultures of rat hepatocytes were used to investigate whether and how an extract obtained from a fermented powder of bean named Lady Joy (Phaseolus vulgaris L.) is able to regulate antioxidant and detoxifying enzymes through the NRF2 pathway, inhibit NF-kB activation, and reduce H</jats:p>

  • 出版日期2015-3