Alstiphyllanines A-D, Indole Alkaloids from Alstonia macrophylla

作者：Hirasawa Yusuke; Arai Hiroko; Zaima Kazumasa; Oktarina Rice; Rahman Abdul; Ekasari Wiwied; Widyawaruyanti Aty; Indrayanto Gunawan; Zaini Noor Cholies; Morita Hiroshi^*

来源：Journal of Natural Products, 2009, 72(2): 304-307.

DOI：10.1021/np8007107

Four new alkaloids, alstiphyllanines A-D (1-4), were isolated from Alstonia macrophylla, and their structures were determined by MS and 2D NMR analyses. Alkaloids 1-4 showed moderate antiplasmodial activity against Plasmodium falciparum and vasorelaxant activity against phenylephrine-induced contraction of isolated rat aorta.

• 出版日期2009-2